A super-villain from New Tek City. Dr. Plague was engaged in battle with the Chaotix Crew during the first part of Doomsday. All of his henchmen had been defeated and were being rounded up by the police, but the crazed doctor would not go down so easily. He presented several vials filled with a lethal viral weapon, each one filled with enough of the virus to wipe out the whole city. Plague threw the vials into the air, but Sonic managed to catch all of the falling vials. His ace-in-the-hole unsuccessful, Dr. Plague was arrested.